{"id":3803,"date":"2022-12-21T12:23:54","date_gmt":"2022-12-21T10:23:54","guid":{"rendered":"https:\/\/hhac.de\/services\/dissolution-testing\/"},"modified":"2024-07-29T15:55:53","modified_gmt":"2024-07-29T13:55:53","slug":"dissolution-testing","status":"publish","type":"page","link":"https:\/\/hhac.de\/en\/services\/dissolution-testing\/","title":{"rendered":"Dissolution testing"},"content":{"rendered":"\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-cjs6xt-d300f49bf73fae47bd99622a1fad0467\">\n.avia-section.av-cjs6xt-d300f49bf73fae47bd99622a1fad0467{\nbackground-color:#ffffff;\nbackground-image:unset;\n}\n<\/style>\n<div id='av_section_1'  class='avia-section av-cjs6xt-d300f49bf73fae47bd99622a1fad0467 main_color avia-section-default avia-no-border-styling  avia-builder-el-0  avia-builder-el-no-sibling  avia-bg-style-scroll container_wrap sidebar_right'  ><div class='container av-section-cont-open' ><main  role=\"main\" itemprop=\"mainContentOfPage\"  class='template-page content  av-content-small alpha units'><div class='post-entry post-entry-type-page post-entry-3803'><div class='entry-content-wrapper clearfix'>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-sz2mo1-8322eb590346c3f379c2641f03c1ddb2\">\n.flex_column.av-sz2mo1-8322eb590346c3f379c2641f03c1ddb2{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-sz2mo1-8322eb590346c3f379c2641f03c1ddb2 av_one_half  avia-builder-el-1  el_before_av_one_half  avia-builder-el-first  first av-break-at-tablet flex_column_div av-zero-column-padding '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-hj9g1-e90cb47a778083ab1e5e98a17be92aed\">\n.avia-image-container.av-hj9g1-e90cb47a778083ab1e5e98a17be92aed 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https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-03-hhac-labor-dr-heusler-1497x1500.jpg 1497w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-03-hhac-labor-dr-heusler-705x705.jpg 705w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><\/div><\/div><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-pbvc35-ddd3d5360200f787abbfc97c86a614dc\">\n.flex_column.av-pbvc35-ddd3d5360200f787abbfc97c86a614dc{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-pbvc35-ddd3d5360200f787abbfc97c86a614dc av_one_half  avia-builder-el-3  el_after_av_one_half  el_before_av_one_full  av-break-at-tablet flex_column_div av-zero-column-padding '     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-on7zn5-dc8d18554fd3dc699633c4cd01f155c5\">\n#top .av_textblock_section.av-on7zn5-dc8d18554fd3dc699633c4cd01f155c5 .avia_textblock{\ncolor:#b8b9bb;\n}\n<\/style>\n<section  class='av_textblock_section av-on7zn5-dc8d18554fd3dc699633c4cd01f155c5'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock av_inherit_color'  itemprop=\"text\" ><h3>BRIEFLY EXPLAINED<\/h3>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-mup8td-ae3cef27d1369a14f30c39ab18b3a8ea\">\n#top .hr.hr-invisible.av-mup8td-ae3cef27d1369a14f30c39ab18b3a8ea{\nmargin-top:-50px;\nheight:1px;\n}\n<\/style>\n<div  class='hr av-mup8td-ae3cef27d1369a14f30c39ab18b3a8ea hr-invisible  avia-builder-el-5  el_after_av_textblock  el_before_av_heading '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b\">\n#top .av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b{\npadding-bottom:30px;\nfont-size:50px;\n}\nbody .av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b .av-special-heading-tag .heading-char{\nfont-size:25px;\n}\n#top #wrap_all .av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b .av-special-heading-tag{\nfont-size:50px;\n}\n.av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b .av-subheading{\nfont-size:15px;\n}\n\n@media only screen and (min-width: 480px) and (max-width: 767px){ \n#top #wrap_all .av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b .av-special-heading-tag{\nfont-size:30px;\n}\n}\n\n@media only screen and (max-width: 479px){ \n#top #wrap_all .av-special-heading.av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b .av-special-heading-tag{\nfont-size:30px;\n}\n}\n<\/style>\n<div  class='av-special-heading av-lbxmjnsj-4e3d072680ba29023bc3c5401aa4fb0b av-special-heading-h1 blockquote modern-quote  avia-builder-el-6  el_after_av_hr  el_before_av_textblock  av-inherit-size'><h1 class='av-special-heading-tag'  itemprop=\"headline\"  >Dissolution testing<\/h1><div class=\"special-heading-border\"><div class=\"special-heading-inner-border\"><\/div><\/div><\/div><br \/>\n<section  class='av_textblock_section av-lbxmjwnd-512228ca57bf4724fabdba5146c89574'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>For dissolution testing, we have a <strong>wide range of (high-end) laboratory equipment<\/strong> from different manufacturers, including &#8220;basket&#8221; and &#8220;paddle&#8221; apparatus, \u201crotating cylinders\u201d for testing of patches, and special equipment specified in some monographs. We also benefit from our <strong>many years of experience<\/strong> in validation concerning requirements outside of Europe (e.g. Japanese area of application).<\/p>\n<p>The tests can be carried out both <strong>automatically<\/strong> and <strong>manually<\/strong>. The use of buffer solutions containing surfactants or enzymes is also possible.<\/p>\n<\/div><\/section><br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-k3ghzl-778bcba52a9ca6bc0196cf6a4fcc2726\">\n#top .hr.hr-invisible.av-k3ghzl-778bcba52a9ca6bc0196cf6a4fcc2726{\nheight:20px;\n}\n<\/style>\n<div  class='hr av-k3ghzl-778bcba52a9ca6bc0196cf6a4fcc2726 hr-invisible  avia-builder-el-8  el_after_av_textblock  el_before_av_button '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n<div  class='avia-button-wrap av-if1uy9-846ee5be908c79c3da2b1cd7ff3bf177-wrap avia-button-left  avia-builder-el-9  el_after_av_hr  avia-builder-el-last '>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-if1uy9-846ee5be908c79c3da2b1cd7ff3bf177\">\n#top #wrap_all .avia-button.av-if1uy9-846ee5be908c79c3da2b1cd7ff3bf177{\nbackground-color:#0c8a7b;\nborder-color:#0c8a7b;\ncolor:#ffffff;\n-webkit-transition:all 0.4s ease-in-out;\n-moz-transition:all 0.4s ease-in-out;\n-ms-transition:all 0.4s ease-in-out;\n-o-transition:all 0.4s ease-in-out;\ntransition:all 0.4s ease-in-out;\n}\n<\/style>\n<a href='#kontakt'  class='avia-button av-if1uy9-846ee5be908c79c3da2b1cd7ff3bf177 avia-icon_select-no avia-size-x-large avia-position-left'  ><span class='avia_iconbox_title' >Request now<\/span><\/a><\/div><\/p><\/div><div class='flex_column av-7t7xk1-cd67fd35b08d9060c5e1f9b0277bb1a7 av_one_full  avia-builder-el-10  el_after_av_one_half  el_before_av_one_full  first flex_column_div column-top-margin'     ><p>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5mffcx-320060517214dbdbfd14bc2997ed0aa6\">\n#top .hr.hr-invisible.av-5mffcx-320060517214dbdbfd14bc2997ed0aa6{\nheight:30px;\n}\n<\/style>\n<div  class='hr av-5mffcx-320060517214dbdbfd14bc2997ed0aa6 hr-invisible  avia-builder-el-11  el_before_hhac_cta_bar  avia-builder-el-first '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><br \/>\n\n<div class=\"hhac-cta-bar\">\n\t<div class=\"hhac-cta-bar__heading\">\n\t\tWe will gladly <span class=\"md-block\">advise you<\/span>\t<\/div>\n\t<div class=\"hhac-cta-bar__email\">\n\t\t<div class=\"hhac-cta-bar__label\">Email<\/div>\n\t\t<a href=\"mailto:hhac@hhac.de\" class=\"hhac-cta-bar__link\">hhac@hhac.de<\/a>\n\t<\/div>\n\t<div class=\"hhac-cta-bar__phone\">\n\t\t<div class=\"hhac-cta-bar__label\">Phone<\/div>\n\t\t<a href=\"tel:+497249913020\" class=\"hhac-cta-bar__link\">+49 7249 91302-0<\/a>\n\t<\/div>\n\t<div class=\"hhac-cta-bar__action\">\n\t\t<a href=\"https:\/\/hhac.de\/en\/contact\/\" class=\"hhac-cta-bar__button\">Contact<\/a>\n\t<\/div>\n<\/div>\n<br \/>\n\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-a64ox-2dbcc764236965666ae4b5486fbe4f1e\">\n#top .hr.hr-invisible.av-a64ox-2dbcc764236965666ae4b5486fbe4f1e{\nheight:30px;\n}\n<\/style>\n<div  class='hr av-a64ox-2dbcc764236965666ae4b5486fbe4f1e hr-invisible  avia-builder-el-13  el_after_hhac_cta_bar  avia-builder-el-last '><span class='hr-inner '><span class=\"hr-inner-style\"><\/span><\/span><\/div><\/p><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-8llvoh-386ab45204ca0ba30e3915e2b1dfdef3\">\n.flex_column.av-8llvoh-386ab45204ca0ba30e3915e2b1dfdef3{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-8llvoh-386ab45204ca0ba30e3915e2b1dfdef3 av_one_full  avia-builder-el-14  el_after_av_one_full  el_before_av_one_half  first flex_column_div av-zero-column-padding column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-lbxmm9w6-ddb2f8aa19251ee2d3991079c9ec882f\">\n.avia-image-container.av-lbxmm9w6-ddb2f8aa19251ee2d3991079c9ec882f img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-lbxmm9w6-ddb2f8aa19251ee2d3991079c9ec882f .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-lbxmm9w6-ddb2f8aa19251ee2d3991079c9ec882f av-styling- avia-align-left  avia-builder-el-15  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-3093 avia-img-lazy-loading-not-3093 avia_image ' src=\"https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler.jpg\" alt='' title=''  height=\"779\" width=\"2000\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler.jpg 2000w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-300x117.jpg 300w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-1030x401.jpg 1030w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-768x299.jpg 768w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-1536x598.jpg 1536w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-1500x584.jpg 1500w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-hhac-labor-dr-heusler-705x275.jpg 705w\" sizes=\"(max-width: 2000px) 100vw, 2000px\" \/><\/div><\/div><\/div><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-p2lyp-79363affa6c4470e96580995f1342ff4\">\n.flex_column.av-p2lyp-79363affa6c4470e96580995f1342ff4{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-p2lyp-79363affa6c4470e96580995f1342ff4 av_one_half  avia-builder-el-16  el_after_av_one_full  el_before_av_one_half  first av-break-at-tablet flex_column_div av-zero-column-padding column-top-margin'     ><section  class='av_textblock_section av-lbxmkver-6ddf478375b52d8c9b9fe415f43b4eeb'  itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/CreativeWork\" ><div class='avia_textblock'  itemprop=\"text\" ><p>Under these conditions, different dosage forms can be analyzed with <strong>unchanged<\/strong>, <strong>prolonged<\/strong> or <strong>delayed release of active pharmaceutical ingredients<\/strong>, even with high sample throughput. This also applies to dissolution profiles &#8211; ranging from short-term profiles with five-minute samples to long-term profiles with run times of up to 24 hours.<\/p>\n<p>In addition, we develop and validate methods for dissolution testing and analytical detection of the active pharmaceutical ingredients to be determined using HPLC, GC, UV\/Vis spectrophotometric or titrimetric measurement.<\/p>\n<p>Our unique strength lies in our <strong>long-standing teamwork<\/strong>. This provides the basis for the precise completion of even extensive projects in a short time and guarantees a smooth workflow even with high sample volumes. Whether in daily routine operations or development of pharmaceutical methods, the rapid transmission of our analytical results enables us to maintain our customers&#8217; <strong>workflow<\/strong> at every stage.<\/p>\n<p>Of course, on demand we also provide dissolution testing under <strong>specific conditions<\/strong>: e.g. within our light protected area lighted with red or yellow light or in our laboratory for <strong>highly active substances<\/strong>.<\/p>\n<\/div><\/section><\/div>\n<style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-5yzo81-ee723bba5c76543addc3e0af59ac2087\">\n.flex_column.av-5yzo81-ee723bba5c76543addc3e0af59ac2087{\n-webkit-border-radius:0px 0px 0px 0px;\n-moz-border-radius:0px 0px 0px 0px;\nborder-radius:0px 0px 0px 0px;\npadding:0px 0px 0px 0px;\n}\n<\/style>\n<div class='flex_column av-5yzo81-ee723bba5c76543addc3e0af59ac2087 av_one_half  avia-builder-el-18  el_after_av_one_half  avia-builder-el-last  av-break-at-tablet flex_column_div av-zero-column-padding column-top-margin'     ><style type=\"text\/css\" data-created_by=\"avia_inline_auto\" id=\"style-css-av-r0q1tt-e0b7520f8fdffe1d8d1d0274d6707f76\">\n.avia-image-container.av-r0q1tt-e0b7520f8fdffe1d8d1d0274d6707f76 img.avia_image{\nbox-shadow:none;\n}\n.avia-image-container.av-r0q1tt-e0b7520f8fdffe1d8d1d0274d6707f76 .av-image-caption-overlay-center{\ncolor:#ffffff;\n}\n<\/style>\n<div  class='avia-image-container av-r0q1tt-e0b7520f8fdffe1d8d1d0274d6707f76 av-styling- avia-align-left  avia-builder-el-19  avia-builder-el-no-sibling '   itemprop=\"image\" itemscope=\"itemscope\" itemtype=\"https:\/\/schema.org\/ImageObject\" ><div class=\"avia-image-container-inner\"><div class=\"avia-image-overlay-wrap\"><img decoding=\"async\" class='wp-image-3095 avia-img-lazy-loading-not-3095 avia_image ' src=\"https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler.jpg\" alt='' title=''  height=\"2355\" width=\"2370\"  itemprop=\"thumbnailUrl\" srcset=\"https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler.jpg 2370w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-300x298.jpg 300w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-1030x1023.jpg 1030w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-80x80.jpg 80w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-768x763.jpg 768w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-1536x1526.jpg 1536w, https:\/\/hhac.de\/wp-content\/uploads\/2023\/01\/wirkstofffreisetzung-dissolution-02-hhac-labor-dr-heusler-2048x2035.jpg 2048w, 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clearfix'>\n","protected":false},"excerpt":{"rendered":"","protected":false},"author":13,"featured_media":0,"parent":3781,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-3803","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/pages\/3803","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/comments?post=3803"}],"version-history":[{"count":0,"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/pages\/3803\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/pages\/3781"}],"wp:attachment":[{"href":"https:\/\/hhac.de\/en\/wp-json\/wp\/v2\/media?parent=3803"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}